Heavy metals testing by ICP-MS offers detection limits down to ppb and ppt levels on most matrices. If you have limited sample size heavy metals testing by ICP-MS is the method of choice.
ICP-MS is a very sensitive technique, having the lowest detection to ppb and ppt levels.
Allows small volumes to be quantified easily
Less waste to dispose
The technique has definitive, multiple isotope identification (less prone to interferences)
Provides a rapid screening method for real pharmaceutical samples
Good agreement with fully quantitative analysis